questions about the eight gates in naruto ?

ok i have asked about the Sharingan and Rinnegan but this time i like to know more about the Eight Gates i know everytime you open them you get stronger, faster and put ou more chakra and your body gets more messed up muscles start to rip and tare and other stuff i know to open the 8th gate you have to puncher your heart but what if someone had a healing factor like First Hokage, Tsunade or Sakura Haruno or what if someone like Wolverine had the eight gates ?

i was also thinking what if someone like Mr. Immortal had the eight gates or Naruto Uzumaki since he used his sage jutsu to saved Might Guy from his fate after he opened all the when he fought Madara Uchiha

@otaconmgs: Think of it as a kaioken with 8 gears.

@otaconmgs:

but what if someone had a healing factor like First Hokage, Tsunade or Sakura Haruno or what if someone like Wolverine had the eight gates ?

They'll survive

Can anyone learn 8G? Or its heriditary/ needs certain gene?

@se7ensun: Anyone can learn it with training.

Anyone with good regeneration can survive it though i would postulate an argument that extreme chakra usage might hamper that regeneration.

This sounds right