How would you think the quality and overall enjoyment of Comic Books would be if they were written realistically? Or if the authors at least had some basic knowledge of biology, chemistry, physics, mathematics, etc? Like their knowledge wasn't so great that comics would be no fun, but enough that things wouldn't be ridiculous.
I'd think Spiderman would either be dead, or made in a genetically modified lab.
Flash would be speed of light at most (only cause the speed force. His base speed with out it at most would be mach 2)
Superman would be a 500 tonner at most (only cause he was born on a planet with a far greater gravity) and an Atomic Bomb would be able to do some serious damage(like being put in a 5 year coma type damage), or even kill.
Joker would be dead. Any villain put in Arkham would stay for substantial amount of time (like 5 years, not just break out issues later).
Only magic or cosmic beings would be world buster level and insanely fast, strong, and durable. Thor & SS would be a God on SA Superman's level. If your just some alien or metahuman, than no.
That's just my opinion. Whats yours?