The Gods of Destruction vs Dragonball Super's Strongest

There's two ways to look at it.

First - by feats. That way team 2 stomps. There's only one GoD with some actual feats, Beerus, others are either completely featless or neigh featless. If we go by feats there is just no way to even try and justify team 1 winning.

Second - by trying to look at the characters from lore-wise perspective, at implied power levels for example. That way GoDs stomp. There are only 2 fighters who were directly said to be on the level of gods of destruction so far - Toppo and Jiren. UI Goku just has one of the abilities of some GoD's and the likes if Kefla and Zamasu are PROBABLY at similar level of sheer power but we can only guess. Anyway it doesn't matter. There are 12 GoD's here and only 10 fighters, only 2 of which are so far on GoD level. This makes it a stomp.

1. Jiren is stronger than any God of Destruction, and Hit was able to give him some trouble. Hit can do the same to a God.
2. Monaka is stated to be a threat to a God of Destruction in the Manga.
3. Toppo can go toe to toe with a God of Destruction.
4. Jiren can destroy a God of Destruction.
5. Vegeta and Goku are able to compete with God tier power.
6. Trunks destroyed someone who was overtaking the entire Multiverse. Zeno had to intervene because nobody could stop him.
7. Vegetto was able to overpower someone who had the potential to overtake the Multiverse.
8. Kefla has the feats and statements to suggest that she's on a similar level of power as a God.

Just to hit on your first point, no one ever said Jiren can defeat any one of the GoDs. He beat Belmond, that's it, and we don't know how close it was. Not all of the GoDs are of the same power level, and according to the manga they each have their own unique abilities. Beerus can react to most attacks instinctively.

If we take Vados' statement about Champa and Beerus seriously, then Beerus is stronger. Meaning the GoDs have different power levels.

The difference between Champa and Beerus is negligible and the only actual difference that was implied to have existed in the Manga was the weight difference, which is how Beerus would defeat him in hand to hand combat.

1. It's been strongly implied, even outright stated, that Jiren has been holding back this entire time. When he threw the purposely missed punch that would have knocked Goku right off the edge, Belmond state's that this is a serious Jiren, yet only a casual attack from such. Goku was so overwhelmed by the sheer force of the blow he forgot how to use Super Saiyan Blue for a second. So up until that point, and probably after the encounter, Jiren has been fooling around. And that includes his fight with Hit. I think a good indicator is when his red aura starts flaring. Once against UI Goku, and once when he was almost tricked into a ring-out.

2. Sure

3. He has the power of a God, but can't properly wield it yet, as his inexperience leads him to have to charge up. Also, his speed doesn't seem to be boosted at all, considering he can't even tag Android 17. 1v1 against any other Hakai user, Toppo would likely lose.

4. Absolutely no evidence behind this. Jiren can defeat his God. Not any God. And, based off Beerus taking on all the Gods in the Manga or Vados stating Beerus to be superior to Champa in the anime, we can obviously see power discrepancies between immortal beings.

5. Mmmm, without UI probably not. Royal Blue doesn't have enough feats yet, and he seems to be getting manhandled by God-Lite Toppo in the preview. Any other form gets fodderized.

6. I call plot device on this. He barely had any energy to power his sword. How does like 2 dozen human survivors have greater power than Vegito?

7. It was a pretty even fight, no decisive blows. Sure, Vegito landed many more attacks, but Zamasu tanked them without too much physical strain and no lasting damage. Also, if you include Zamasu's immortality then he solos. Otherwise he's pretty fodder as his feats are quite limited.

8. What? How? She could one-shot UI Goku, but his UI only boosts speed and dodging ability, not attack or durability, so it's akin to one-shotting a super tired, super worn out, already damaged SSG-SSB Goku. Kefla stated she felt like she could destroy the universe, but I always say I feel like I could eat a horse. Spoiler, I've never eaten a horse. Also, Caulifa (and Kefla by extension) loves exaggerating. She was adamant to the very end she could pulverize Goku, despite losing to SS2, then SS God, then Ultra Instinct. Feat wise, her pure stage destruction overall completely pales in destruction to what a true nigh-God level Toppo did as a side effect of his attack on Frieza.

GoDs. Most of them are at GoD level, but the GoDs have the advantage of being more versatile.