Syonide was only able to hurt Thunder because Thunder relaxed her powers (and Syonide was paying attention to her breathing). Luke's powers are always active, so he's not going to give them that opening. He's just always going to be too durable for them to legitimately hurt
@arcus1: Syonide may not be able to hurt him but she can tire him out. Thunder only hurt her because of claps and stomps. Which means Cage has to punch her and we seen her get up from the claps and stomps so she may be able to get up from a punch from him. So basically Syonide skill will allow them this win.