Kaido blitzed luffy who has reacted to pure light beams shot from pacifista which were harnessed from kizaru so I wouldn't say kaido is at a massive speed disadvantage however kizaru is the strongest marine so neither is significantly outclassed.
Kizaru can't win this. In character he'd never try and take on Kaido by himself unless he had no other option.
Although the guys comparing Kizaru to Luffy should stop. All of The Admirals are capable of one shotting Luffy. Luffy is no where near the Admirals level of power yet. Right now every Admiral would beat Luffy without using full effort.