Any gear for the Chief? Anyway the Chief should win this low difficulty the spartan armor can tank nukes and can tank falling back into earths orbit without problems. Chief is also highly skilled and has striking feats that could probably put Deku down his reaction speed is also insane. Chief 8/10
Master Chief in a vastly inferior armor and far less experienced was able to react to a air to surface missile. I feel that's sufficient to say he won't be speedblizted, especially with the massive skill gap. He also has some crazy durability, which I feel would make it hard for Deku to make a dent.
The issue comes in when we talk about offense. Most of Chief's weapons are, well, guns. Things Deku can easily avoid and has done repedeatly. Unless he gets Covenant or Forerunner gear, he doesnt have a way to really hurt Deku (unless I'm forgetting some striking feats).
EDIT: Now I remember. A teenage John weeks off his surgery and without any combat experience or even MK1 Spartan armor ripped apart a big metal mech like it was a doll.