Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Dr. Stephen Strange was once a gifted but egotistical surgeon who sought out the Ancient One to heal his hands after they were wounded in a car accident. Instead, the Ancient One trained him to become Master of the Mystic Arts and the Sorcerer Supreme of Earth.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Clea is the heroic daughter of Umar and the niece of Dormammu. She is also Doctor Strange's estranged wife and was the ruler of The Dark Dimension until her Uncle usurped her throne and regained his.
After being bombarded with a massive dose of gamma radiation while saving a young man's life during an experimental bomb testing, Dr. Robert Bruce Banner was transformed into the Incredible Hulk: a green behemoth who is the living personification of rage and pure physical strength.
A former KGB agent Natasha Romanova, better known as Black Widow, is one of the best agents S.H.I.E.L.D. has ever had. She's a longtime member of the Avengers as well as the leader of the short-lived Los Angeles-based superhero team called the Champions.
Ringmaster (Maynard Tiboldt) is a circus villain who gains control over people by hypnotizing them with his hat.
Kyle Richmond was a thrill-seeking playboy who became the costumed adventurer Nighthawk. Starting out as a villain, Richmond soon found altruism a greater pursuit. As Nighthawk, he became mainstay of the Defenders, and has also acted alongside the Squadron Supreme, the Redeemers, the Thunderbolts and the Initiative.
Man-Thing is a powerful swamp creature and guardian of the Nexus of all Realities. He was once human and turned himself into a monster as a last act of defense and a way too avoid his serum falling in the wrong hands.
Howard is a cigar-smoking anthropomorphic duck who lived in New Stork City on the planet Duckworld (in a parallel dimension). He was transported to and became trapped on our world, where he became close friends with Beverly Switzler. Most people of Earth simply do not believe that he is a talking duck.
The Asgardian goddess Brunnhilde is one of Asgard's mightiest warriors and the leader of the Valkyrior, Odin's choosers of the slain. Known simply as "Valkyrie" outside of Asgard, she is a long-time member of the Defenders and more recently also a member of the Avengers.
A young woman whom encountered the Man-Thing. She became a powerful and skilled sorceress with extensive knowledge of magic and arcane lore. She is also the cousin of Johnny Blaze and Dan Ketch.
A somewhat weak member of the Circus of Crime.
Seductive snake charmer and, notably, the first villainess Spider-Man ever faced.
Dakimh is a powerful sorceror of earth's dimension.
Beverly Switzler is the closest thing Howard the Duck has to a sidekick and friend.
Doctor Bong is a former journalist turned mad scientist with an unhealthy obession for Beverly Switzler, who he first met in a life-drawing class. He's primarily an enemy of Howard the Duck.
Mary Jane Watson is a major love interest of Peter Parker aka Spider-Man. She married him but didn't(!), now she's one of the few people who know who he is, and still supports him as a close friend and confidante. Currently, Mary Jane and Peter have reconciled their relationship and she no longer seems to work for Stark Industries.
Thog the Netherspawn is an ancient demon lord from another dimension and major enemy of the Man-Thing.
Denying his infernal heritage, the Son of Satan uses his abilities for the betterment of mankind, but has at times succumbed to his darker, demonic side, even clashing brutally with the forces of both Heaven and Hell.
As a child, Matt Murdock was blinded by radioactive waste while trying to save an elderly stranger about to get hit by a truck carrying the dangerous material. In turn, his other senses were heightened to superhuman sharpness and he gained a form of "radar sense". By day, he is a successful trial lawyer; but by night, he guards Hell's Kitchen as Daredevil: the Man Without Fear.
Howard the Duck villain with an obsession for harvesting kidneys.
A former member of the Circus of Crime, Griffin is a gamma-irradiated member of the Gamma Corps.
Luigi and his brother Ernesto are the Flying Gambonnos in the Circus of Crime.
A man-turned-ape who sold swapland. Yes, it could only be another Howard the Duck foe.
The wisping-- I mean lisping psychic ally of Howard the Duck. Like all Howard the Duck characters, she's a little... special in the head.
Narcoleptic split-personality sleepwalker, eccentric artist, and a good friend of Howard the Duck.
Owner of a diner and employer of Howard the Duck for some time. He is also Beverly Switzler's uncle.
A nurse who worked for Hitler's Dentist, she was into the whips and chains. A foe of Howard the Duck.
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