Star Trek Canon Special Note
Not everything listed in the origin is Canon. That is because only television shows and movies are considered canon. This being a comic website there are many things here that are not canon. So unless it is contradicted in film it should be listed as part of the character biography.
The Enterprise was most famous for the crew of it's last Captain (James Kirk) but there were two other Captains that commanded the ship before him. The First Captain was Robert April, then Christopher Pike. Each Captain had a notable crew.
The most notable crew under Pike was, First Officer Number One, Spock, Jose Tyler, Mia Colt, Sita Mohindas, Gabrielle Carlotti, Communications Officer Nano, Dr. Phillip Boyce and Moves With Burning Grace. Of this Crew Spock was the only one to serve under Captain Kirk. Kirk had many other officers serve during his command of the Enterprise. Most notable were First and Science Officer Spock, Dr. Leonard McCoy, Hikaru Sulu, Nyota Uhura, Montgomery Scott, Pavel Checkov, Janice Rand, Christine Chapel, Willard Dekker, and Ilia.
The creation of the Enterprise Crew was for the television show Star Trek. It was created by Gene Roddenberry. The Crew of the Enterprise changed with the creation process as well as the availability of the actors. Many were not even given full names on any of the films but were many were given as concepts. Robert April was the original name for the Captain but that was changed to Christopher Pike before the first episode was filmed. The crew in the first pilot episode was only known as Christopher Pike, Number One, Spock, Tyler, Boyce and Colt.
The first pilot showed promise but changes were requested and the very rare chance for a second pilot was requested. One of the decisions in order to get the second pilot was to get rid of the Number One or Spock character. As Gene said he kept Spock and married the other. Meaning he married the actress Majel Barrett that played the part. This new crew was composed of James Kirk, Spock, Mark Piper, Scott, Sulu, Alden and Yeoman Smith.
Finally the show was picked up and the crew was composed of most of the actors known today being James Kirk, Spock, Lenard McCoy, Uhura, Sulu, Montgomery Scott and Janice Rand. As the seasons went on crew members like Christine Chapel and Pavel Chekov were added and Rand left when the actress who played her Grace Lee Whitney quit.
In the 1970's characters were added from the cartoon show. These were alien's who would be too hard to depict on the live action show. They were M'Ress, and Arex. Then the show started work on a second live action show that would have added characters, Willard Dekker, Ilia and a Vulcan named Xon. The show however was tuned into the first movie and the Xon character was dropped. In the second film the character of Saavik was added and she would be the last on the main crew as the ship was destroyed by the third movie. This excludes the many regular crew that would be depicted in comics.
In a major story arch in Star Trek: Early Voyages the crew is different, as things were changed in the timeline due to the disappearance of a simple yeoman named Mia Colt. Only three of the seven main officers were part of the crew. They were Uhura, Spock, and Sulu. In this universe Kirk and Scott were members of a cargo ship called the Bounty and Chekov was serving aboard the U.S.S. Excelsior. Where McCoy was in this universe is unknown.
New crewmembers were Captain Christopher Pike, Jose Tyler, Gabrielle Carlotti and Saavik. Fortunately, everything is set back to normal when Colt is returned to her timeline.