The secret of the mutation of Earth is revealed against the backdrop of an even bigger mystery: the truth behind the universe itself! The battle for New York begins as Spider-Man's daughter, Venom, takes on the Iron Maiden in Times Square while Clea, the Sorceress Supreme, clashes with Thor, the Goddess of Thunder! Meanwhile, Luna of the Inhumans makes a terrible self-discovery! Plus: Captain America recruits the World Super Powers?but why? And last but not least, it's the Skull vs. the Goblin for leadership of America!