Upon arriving at a primitive village, science fanatic Senku schemes to recruit the villagers to help him bring about a new civilization based on science! His first target is a young, inquisitive villager named Chrome, whom Senku wins over by defeating him in a battle of wits. Their first big task? To find a cure for Kohaku's older sister and the village shamaness—Ruri!
- Z=17: Nasty Looks
- Z=18: Sorcery Showdown
- Side Story: Chrome vs. Senku! Arithme-Battle!!
- Z=19: Two Million Years of Being
- Z=20: Stone Road
- Z=21: Dawn of Iron
- Z=22: Survival Gourmet
- Z=23: The Smooth Talker
- Z=24: Lightning Speed!!
- Z=25: By These Hands, The Light of Science
Note: The digital edition (1/1/2019) for this volume was released before the print edition.