Dr. Stephen Strange was once a gifted but egotistical surgeon who sought out the Ancient One to heal his hands after they were wounded in a car accident. Instead, the Ancient One trained him to become Master of the Mystic Arts and the Sorcerer Supreme of Earth.
Tyrone Johnson is the "dark" half of the vigilante duo known as Cloak and Dagger. After a drug-related experiment awakened his powers, he became a living personification of darkness. Cloak is the Yin to his partner Dagger's Yang. Superheroes of the streets, Cloak and Dagger wage a war against dangerous drugs and drug-related crimes.
Tandy Bowen is the "light" half of the vigilante duo known as Cloak & Dagger. After a drug-related experiment awakened her powers, she became a living personification of light, with the ability to generate super-luminosity at will and use it both offensively and defensively.
Wong is Dr. Strange's assistant, friend, and defender. He has helped a number of other heroes, like Spider-Man, by providing them with information.
Clea is the heroic daughter of Umar and the niece of Dormammu. She is also Doctor Strange's estranged wife and was the ruler of The Dark Dimension until her Uncle usurped her throne and regained his.
Nightmare is the ruler of the dream dimension and a co-creator of the Fear Lords. He is a primary enemy to Doctor Strange
Manslaughter is a supervillain in the Marvel Comics universe. He is a psychopathic killer who has fought the Defenders, and later briefly joined their team.
The Asgardian goddess Brunnhilde is one of Asgard's mightiest warriors and the leader of the Valkyrior, Odin's choosers of the slain. Known simply as "Valkyrie" outside of Asgard, she is a long-time member of the Defenders and more recently also a member of the Avengers.
One of the Eternals of Earth whom helped the Defenders defeat the spirit of the Dragon of the Moon that had taken over Defenders member Moon Dragon. He died, but was, with the other Defenders, ressurected by Doctor Strange
Rintrah is an alien sorcerer in training who is studying under Dr. Strange.
The beautiful and heroic Atlantean warrior is a member of the Defenders. Like Prince Namor: The Sub-Mariner, Andromeda defends her people and the surface dwellers with honor and might. She uses a serum that temporarily allows her to breathe air while on land. She has proven her mettle on both land and sea.
Topaz is a powerful mystic in the Marvel Universe who has unique empathic abilities.
She has adopted to two female forms, one Caucasian and one Indian.
She fights with a group of teens called the Witches.
A powerful black magician and peer of the Ancient One, Kaluu is also a sometimes-ally of Dr. Strange.
Erlik is the god of Death and the underworld in Altaic (Turkic and Mongolian) mythology.
Khats are the demonic servants of Erlic Khan from the Thirty Infernos.
The Water Elemental is a demon of extra-dimensional origin who serves the Chaos Lord, Shuma-Gorath. It has absolute control over the element of water.
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