Dr. Sax was a member of a rock band with Johnny Guitar. One night after a show, Dr. Sax and Johnny Guitar were robbing their manager, but were stopped by the other band members. During the fight Sax's face was burnt by a torch, blinding him.
After being released from prison Dr. Sax was given a saxophone and visor by Techmaster. The saxophone is capable controlling emotions, and the visor restores his sight.
Dr. Sax and Johnny Guitar(now armed with a guitar from Techmaster) went after their former band looking for a little revenge. Dazzler showed up just as they began to torture one of their former band members. Johnny Guitar destroyed her skates with a blast from his guitar, when he fired at her again she used her mutant power to transform sound to light and knocked Johnny out. Sax then tried to use his saxophone on Dazzler, but she absorbed the sound and disintegrated his saxophone. Sax then rushed Dazzler, but she threw a pot of coffee in his face, shorting out his visor. With Sax now blind, it was easy for Dazzler to beat him.
The two would get out of the joint sometime later and both guys decided to start playing in the big leagues. Both men would try to join various criminal crews including the Sinister Six, Brotherhood of Mutants, the Death Throws and even the Circus of Crime but were ultimately denied. His wife, Revonda and their daughter had enough of Johnny and they left him. Johnny would work as a janitor at a local casino but would gamble his paycheck away when he received it. Doc went on disability but the two friends would get small gigs like a wedding or a high school dance from time to time. One day, Johnny would run into Petruski and told him that Norman Osborn was running the Initiative and both men decided to register.
Both men went through training and were assigned to the Shadow Initiative by the Taskmaster. Their first mission was to take back 42 which was the supermax prison in the Negative Zone that was taken over by an army of aliens led by Blastaar. Johnny overheard Taskmaster and Constrictor talking how sorry the new Shadow Initiative was and this team of reformed criminal rejects were to be used as cannon fodder during their initial assault on 42. Johnny would discuss some of his feelings with Trauma and realized nothing is more important to a child as having a father in their life. Johnny wanted to protect his best friend by starting a fight with him and breaking his left hand with a sonic blast. Doc was taken to the infirmary and Johnny received a beating by the Taskmaster. Johnny was still assigned to the 42 mission but his friend remained in the infirmary. Johnny could never tell Doc why he did it but knew it was for the better. Johnny told Doc to give a small diary to his daughter while he left for his first mission. Johnny Guitar and the rest of the Shadow Initiative rushed the super prison once the gates opened and all hell broke lose. Johnny was killed during battle when he was impaled by a piece of metal. Doc reunited with his wife and his three kids.
Doc had a saxaphone whose music could drive people crazy. He also wore goggles that allowed him to see shapes.