Character » Doctor Octopus appears in 2442 issues.
Fabian Stankowicz is a technical whiz who tried to make a name for himself by attacking the Avengers as the Mechano-Marauder. He would eventually reform as Mechanaut and use his talents to assist the Avengers and Captain America.
Trained to be an assassin with her microwave-manipulating mutant powers, Firestar instead grew to be a popular hero. A key former member of New Warriors, now member of the X-Men.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
Weasel worked for Dr. Octopus.
Franklin and Valeria Richards helped their parents to fight Doctor Octopus and his followers.
Octopus once worked with Fusion. However, Octavius simply pretended to be Fusion's follower, beating him half to death.
Galactus is the infamous "Devourer of Worlds" in the Marvel Universe. His powers are nearly omnipotent. He has appointed several entities as his Heralds, imbuing them with the Power Cosmic. He uses energy from the core of planets and universal sources to sustain himself.
After the battle with Guardians of Galaxy, Gargantua, Puff Adder, and Shocker turned against Doctor Octopus.
Military general and diplomat who was taken hostage by Dr. Octopus.
Doctor Octopus was the cause of George's death.
When innocent blood is spilled, a Spirit of Vengeance is born. Dan Ketch transforms into Ghost Rider and nothing will stop him from inflicting pain on all those who have inflicted it on innocent beings. Eventually, Ketch learned to control these transformations. However, it was later revealed that his ancestor was Noble Kale. After some time away, he returned working for Zadkiel.
A founding member of Big Hero 6.
Greg Willis was a normal teenager until a mysterious accident changed his life forever. Now known as the hero Gravity, Willis sets out to make his impact on the Marvel Universe.
Gwen Stacy was the first true love of Peter Parker. She's best known for her tragic death by being thrown off from the Brooklyn Bridge by the Green Goblin. The Earth-65 version is Spider-Gwen who is a major player in the Spider family.
A small time criminal that worked his way up to having his own crime family within the Maggia.
Harry Osborn is the best friend of Peter Parker, the Amazing Spider-Man. His father is Norman Osborn, a global industrialist and billionaire.
Trained by criminals and inspired by heroes, Clint Barton has grown from a troubled youth into one of the greatest heroes on Earth. The world knows him best as Hawkeye: Earth's Mightiest Marksman. A member of the Avengers for many years, he has left the team on occasion because of team friction. But he always returns, ready to face any threat.
A former girlfriend of Matt Murdock AKA Daredevil. She was a former head of the now closed Glenn Industries. She commited suicide after she thought that Matt had ended the relationship.
Henry Sturgess was a shop owner that was murdered by Dr. Octopus.
A young genius who invented Baynax, and became a member, and eventually the leader of the Japanese superhero team Big Hero 6.
Roderick Kingsley became a worthy heir of the Goblin legacy, creating his own identity, of the Hobgoblin, rather than being just another Green Goblin clone.
Honey Lemon is a Japanese superhero and member of the Big Hero 6, who has a power purse in which she has access to another, unknown dimension from which she can pull out all kinds of items.
In a Spider-Man issue, writer Erik Larsen wrote a controversial sequence pitting Doctor Octopus (with his adamantium harness) vs. the Hulk. With this harness Doctor Octopus was able to restrain and knock out the Hulk. In a later confrontation (written by Peter David) Hulk stumbled across Octavius in Vegas and, claiming the last conflict was 'petty larceny', Hulk knocked Doc Ock out with one finger.
The second most powerful member of the Fantastic Four and the younger brother of Sue Richards. Due to an accident caused by cosmic radiation in space, he can manipulate fire, turn his entire body into it and fly. While Johnny is known for his impetuous and sometimes reckless nature, he is also a loyal friend and fearless hero.
Hyperion is Marvel's first Superman pastiche. He is most often associated with the super-team known as the Squadron Supreme and was an Avenger at one point. Though he is one of many active versions across a myriad of alternate universes, Hyperion is still one of the mightiest super-humans in the Marvel Multiverse.
Girls, acne, homework and supervillains. When you're a teenager it pays to be - Invincible. Mark Grayson is the hero Invincible, whom is a Viltrumite/Human hybrid. Mark is one of the greatest heroes on Earth and is the son of Omni-Man. The new emperor of the Viltrum empire is a true hero to the very end.
Doctor Octopus battled Fantastic Four.
The latest in a long line of warriors who wielded the power, Danny Rand is the immortal Iron Fist: protector of the mystical city of K'un Lun. He channels the soul of the dragon Shou-Lao making his fists into powerful weapons. He is among the best, if not the best fighter in the Marvel Universe. He has also been a member of The Defenders and the New Avengers.
Tony Stark was the arrogant son of wealthy, weapon manufacturer Howard Stark. Tony cared only about himself, but he would have a change of heart after he was kidnapped by terrorists and gravely injured. Pressured to create a weapon of mass destruction, Stark instead created a suit of armor powerful enough for him to escape. Tony used his vast resources and intellect to make the world a better place as The Invincible Iron Man. Stark's super hero identity led him to become a founding member of the Avengers.
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