Desiree Winthrop was a model and a friend of Ben Reilly (Scarlet Spider, Spider-Man). She was a frequent visitor to the coffee shop called the Daily Grind.
It was there that she and Ben first met. The two had a strange relationship, in witch Desiree always tried to tell Ben she liked him, without ever really telling him how she fell. Eventually nothing came of it since Ben died by the hands of the Green Goblin.
What has become of Desiree after Ben left the Daily Grind remains to be seen, she has not been seen since.