Kicking off much like the pilot episode of a TV series, DEATH WALKS THE STREETS #0 thrusts readers right into the action in the City of New Marshall. Michael Labou, along with friends Danielle Dante and Malcolm McDermot officially work for IBVM Union Local 666. Unofficially, they're pawns in a much larger game controlled by an International crime syndicate known only as "the organization." When a person of interest suddenly disappears, the trio finds themselves called upon by their employer to track down the man, and bring him in for a face-to-face with local boss Dominick Savini. They soon learn that Peter Moore is being hunted by both man and beast. Meanwhile, a political storm begins brewing, and an ancient enemy returns to walk the streets of New Marshall.