Deadpool takes on a mission to Antarctica, where he finds himself face to face with Sasquatch (Walter Langkowski) of Alpha Flight!!
His assignment is to level a abandoned building, but when setting the device he notices that the station is not so abandoned after all. But, it is too late-the bomb he placed goes off and damages vital equipment. Equipment that pulls Gamma Radiation out of the earth's atmosphere. Now, with the "entire southern hemisphere" in danger, Wilson must battle Sasquatch of Alpha Flight and risk everything to patch the damage he just created.