The techno-organic Blight exist in one timeline inhabited by the Legion of Super-Heroes. This scientifically advanced species sought the secret of immortality. In their mad quest, the Blight were turned into a race of perpetually decaying beings and, using the teleportation skills of the alien Doda (beings who could teleport themselves across the galaxy to seed new worlds), spread that decay across the universe.
In the 31st century, the Blight, led by Atrophos, their chief scientist and engineer, drained the life energy from dozens of worlds. This hostile, malicious race first came into contact with a Legion of Super-Heroes cruiser when the aliens entered United Planets space.
Using the cruiser's Stargate technology, the Blight's corrosive power spread to several planets and they eventually took control of Earth. The Blight enslaved many Legionaires in their search for Mon-el, whose powers they believed would give them immortality and end their existence as decaying beings. However, the Legion were able to destroy the Blight by teleporting their Doda captives across the known universe to revitalise the life forces drained by the techno-organic parasites. Without the Doda, the Blight were unable to teleport or spread their putrefication throughout the galaxy any more.