The mysterious mutant known only as Bishop is a man out of time. Trapped in our age and forced to come face-to-face with his era¹s legends, he has recently been lost to his teammates in the depths of space. Now Bishop has at last returned to the X- Men on the eve of their darkest hour, as they have been ruptured by the events of "The Shattering!" But events soon send him in search of his missing sister Shard... and on a trail of destruction that eventually hurls him into the future! Finding himself in a strange and unfamiliar place, our hero discovers that Earth is now a place that resembles the middle ages: primitive villages and clans have replaced cities, the fight for survival has replaced law and order... civiliziation as we know it has fallen! Alone and confused, Bishop must stop the man that has brought him here before the madman claims the entire world as his own! But who are the strange children who seem to possess mutant powers of their own? What do they want of him, and why do they wear the mutant "M" marking over their eyes? Finally, how does the memory of the X-Men live on, and why do the people of this era remember the name of Bishop: The Last X-Man?
Bishop has a nightmare of when he had the opportunity to save a group of wayward children, who grew up in a world of fear. He failed to protect them and, because of him, all the children died and his archenemy, Fitzroy, who was the one who endangered the children, escaped. Bishop wakes up from his nightmare and, the next morning, he announces to Storm that he is leaving to find Fitzroy, as with the X-Men disbanded there is no better time than now. However, before he leaves, he gives Storm his X-Men badge to keep safe. Bishop heads to NYC to find his sister, Shard, who left word of how to find her after X-Factor disbanded. He finds his catatonic sister in a poor apartment complex that is empty, except for a boy named Michael. Bishop is able to snap Shard out of her daze. Bishop also finds the apartment’s tenets’ bodies in a bedroom and discovers that Fitzroy has sucked their life energies dry. A temporal portal open and several creatures called Chronotroopers under the command of the Chronomancer attack, but Bishop recharges himself in the basement, where he uses his energy to bring the building down. Unfortunately, at the last minute, Bishop realizes that Michael is still in the building. The Chronotroopers return back to the Chronomancer, leaving Shard alone to mourn her brother’s death. Bishop, however, wakes up in the desert, without Michael, and is harassed by the occupants of a passing coach. The coach is attacked by some robbers named Scorch, Jinx and Nom; the former two wearing the M mark like Bishop’s, except theirs wipes off. Bishop falls unconscious and the coach escapes. Jinx convinces Scorch to let them take Bishop back to their camp, as he has a permanent M on his face, which signifies that he is the one who can change their future. Meanwhile, the regent is attacked by Scorch and his group reports this to the Chronomancer, who kills him. The Chronomancer, who is actually Fitzroy, realizes that Bishop is still alive and has somehow made it to his future.