Annihilus appears in 448 issues.
Adam Warlock is a synthetic being created by human scientists named "The Enclave" to become their ideal template for a new race of humans who would rule the Earth. However, their creation, called "Him," rebelled, turned against them, and went on to become Adam Warlock.
Aegis is one of the Proemial Gods, who are said to prepare all that exists for what is to come. They were created to keep balance in the living universe.
Mystical sorceress and a nanny to Franklin Richards. She was also a teacher to the Scarlet Witch, by whom she was murdered in the end.
A real cliffhanger scene appears at the end of issue 251 when Annihilus seizes Alicia by the throat.
The Norse god of light, noble Asgardian warrior, and biological son of All-Father Odin and All-Mother Frigga, as well as half-brother and good friend of Thor. He is one of the bravest warriors of Asgard.
Bentley 23 is a clone of the Wizard who was liberated from his "father" by the Fantastic Four. He rebels against his evil bloodline as a member of the Future Foundation.
The Beyonder is an immensely powerful extradimensional entity of disputed origin. The Beyonder is the beyond-all and end-all of all things, striven on occasion to be both mankind's greatest savior and threat, in a quest to better understand human nature.
The king of the Inhumans, Black Bolt is cursed and blessed with a quasi-sonic voice. He must remain forever silent, for with the slightest whisper he can destroy cities, and with the loudest screams he can level continents.
Black Dwarf is one of Thanos' generals in the Black Order.
Annihilus is an insectoid being from the Negative Zone. He is a nihilist and a constant threat to life anywhere. He is a longtime foe of the Fantastic Four.
Bobby Lane is a member of Gen 13 with the ability to generate high-energy plasma and manipulate the resulting flames.
A normal girl who got mixed up with Drax the Destroyer. While she possesses no superhuman abilities, she is not to be underestimated. Cammi doesn't seem to be able to filter ideas that would be considered rude before stating them.
During World War II, Steve Rogers volunteered to receive the experimental Super-Soldier Serum. Enhanced to the pinnacle of human physical potential and armed with an unbreakable shield, he became Captain America. After a failed mission left him encased in ice for decades, he was found and revived by the Avengers. Later joining their ranks and eventually becoming the team's leader.
A captain in the Kree militia, Mar-Vell rebelled against a racist tyrannical empire to defend Earth and in so doing became the "Protector of the Universe" known as Captain Marvel. Since his tragic death to cancer, Captain Marvel has inspired many superheroes and heroines and his legacy is still felt throughout the Marvel universe.
Captain Universe is the physical manifestation of the Uni-Power. Once it possesses a host, it grants immense power for the purpose of protecting universal balance.
Dara Ko Eke was held prisoner by Annihilus in the Negative Zone.
As a teenager, Chris Powell discovered an amulet allowing him to don the alien armor of Darkhawk. Belonging to an ancient sect of Shi'ar assassins known as the Fraternity of Raptors, it provides immense protective and fighting power to its wearer along with access to its Datasong which grants the ability to access memories and possible future outcomes of events.
Deathblow is a hero from the Wildstorm Universe, initially thought to be the only member of Team 7 without Gen-Factor powers. It was recently discovered that one of his Gen-Active abilities is immortality.
The very mention of his name makes lesser men tremble! The brilliant scientist whose iron mask conceals his scarred (but once handsome) face! Master of science and sorcery, Victor Von Doom is the monarch of Latveria, attempting the betterment of humanity through world conquest! Unequaled and unrivaled in every manner, Doctor Doom has had many conflicts with both earthly and cosmic super-beings, but he will always be known as the eternal nemesis of Reed Richards and his accursed Fantastic Four!
Els Udonta was held prisoner by Annihilus in the Negative Zone.
Eson the Searcher's sole duty is to seek out specimes for Gammenon to gather.
A social worker turned hero, Sam Wilson's bleak outlook on life was wiped away the day he met Captain America. Using a winged costume and his remarkable combat prowess and avian telepathy, he became the Falcon - defender of Harlem.
Fandral the Dashing is a charter member of the Warriors Three, a trio of Asgardian adventurers consisting of Fandral, Hogun the Grim, and Volstagg the Valiant. They are members of the supporting cast in Marvel's Thor comics and usually provide comic relief and side-adventures.
The Firelord started life as Pyreus Kril on the planet Xander home to the legendary Nova Corps. He was once one of the Heralds of Galactus.
Franklin is the son of Reed Richards and Sue Storm, also known as Mr. Fantastic and Invisible Woman of the Fantastic Four. Franklin is an Omega-level mutant with reality-warping abilities; even at a young age he is one of the most powerful beings in the Universe.
Galactus is the infamous "Devourer of Worlds" in the Marvel Universe. His powers are nearly omnipotent. He has appointed a number of entities as his Heralds, imbuing them with the Power Cosmic. He uses energy from the core of planets and universal sources to sustain himself. He has currently been changed into the Lifebringer, who restores life to the planets Galactus has destroyed.
Kallark, codenamed Gladiator, was once the Praetor of the Shi'ar Imperial Guard, the most faithful servant of the Shi'ar throne. After the Shi'ar-Kree War, with the apparent death of Lilandra and Vulcan, Kallark is elevated to the position of Majestor by consensus of a desperate Shi'ar populace.
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