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Branko , May and Andy are on a mission of utmost importance to find out the true origin of the mutates . The group is joined by special agents Mistral and Kay , two mutates that are part of the community of Hell's Island , Shandra , a powerful telepath , and Yoyo, a monstrous mutant child. And while Mr. Alpha and Skotos move in the shadows, Janine finds out that that Andy's health is in bad conditions, and it is getting worse quickly.

The pre-production title of the issue was "L'ultimo dei mutati", but it was finally published as "Il segreto dei mutati". The preview image in the official site of the publisher still has the former title, and shows a cover that actually does not exist...

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