In a spell gone wrong, Spider-Man and Doctor Strange are tossed in and out of other dimensions!
Dr. Strange confronts Dormammu while the other heroes contains the Mindless One. Deciding to help Strange, Spidey accidentally alters the dynamics of Doc's spell. Intending to destroy both himself and Doemammu, Strange instead cast outside of space and time with Spidey, simultaneously seeing the past and a possible future where Dormammu wins. There, Spidey tries to rescue Mary Jane from a Mindless One but it snaps her neck, killing her. Time switches and he finds at Aunt May's grave observing his middle-aged self. Stuck between time, Spidey simultaneously sees that future self face off against the police even as his past self is about to be bitten by a radioactive spider.