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Son of Wilson and Vanessa Fisk. Took up the identity of The Rose to become a rival to his father, and later became Blood Rose to act as a vigilante who openly fought against his father.
Duplicate of Mary Parker designed to destroy Spider-Man.
A man who would later take the name of Martin Li, was given an experimental drug which eventually allowed him control of some type of black electrical energy resembling a photographic negative.
Shocker is a supervillain originating from Marvel Comics. A self-taught engineer, Herman Schultz created a pair of gauntlets that produces shock waves incorporated into a suit that protects him from the impact of of the blasts. He is a recurring foe of the superhero Spider-Man.
Trained by criminals and inspired by heroes, Clint Barton has grown from a troubled youth into one of the greatest heroes on Earth. The world knows him best as Hawkeye: Earth's Mightiest Marksman. A member of the Avengers for many years, he has left the team on occasion because of team friction. But he always returns, ready to face any threat.
Duplicate of Richard Parker designed to destroy Spider-Man.
Frederick Foswell was a reporter for the Daily Bugle and was also known as the mobster, Big Man. He later died after he bravely sacrificed his life for J. Jonah Jameson. His daughter later took up his Big Man identity.
Uatu is a pre-teen genius who works in Horizon Labs.
Luke Cage, wrongly convicted and unjustly imprisoned, was altered in a failed prison experiment that granted him unbreakable skin and superhuman strength. With his street smarts and unending determination to do right, he fights for the common man! He eventually married Jessica Jones and had a daughter with her.
Sajani worked in Horizon Labs and currently, in Parker Industries. She is the creator of the Reverbium.
A burglar Spider-Man allowed to escape at one point, he would later kill Uncle Ben.
Phil Urich, was a hero who, somewhere along the line, began thinking the universe was against him, leading to a psychotic break. Formerly taking up the mantles of Darkhawk, Green Goblin and Hobgoblin, Urich is now known as the Goblin Knight.
Rumor monger and scandal sheet printer, Dexter Bennett became the latest owner of the Daily Bugle after a hostile buyout of long-time owner J. Jonah Jameson.
Cletus Kassady is a deranged and highly dangerous serial killer and long-time host to the Carnage symbiote.
Jacob Conover was once a Daily Bugle employee and later headed his own criminal empire when he became the third criminal known as the Rose.
Tiberius Stone was a scientist, owner of his own multinational corporation (Viastone) and who then later worked for the Kingpin. He started working for Horizon Labs as a double-agent.
Julia Carpenter is the second heroine to take up the mantle of Spider-Woman, later changing her name to Arachne. After the events of the Grim Hunt she became the new Madame Web and is currently a watcher and guardian of the Spyders.
After being bombarded with a massive dose of gamma radiation while saving a young man's life during an experimental bomb testing, Dr. Robert Bruce Banner was transformed into the Incredible Hulk: a green behemoth who is the living personification of rage and pure physical strength.
Once Michael Morbius was a world-renowned bio-chemist, dying of an unknown blood disease and desperately searching for a cure. He found that cure, but, in turn, it afflicted him with a curse far worse than any possible disease; the curse of the blood-sucking night-beast; the curse of the Living Vampire.
Fellow student and brief girlfriend of Spider-Man
Spider-Woman is an Avenger and spy who got her powers from an experiment gone wrong. She has been an agent of S.H.I.E.L.D. and S.W.O.R.D., as well as a Private Investigator. Jessica was a crucial character in Marvel's Secret Invasion comic book event.
Carnage is the offspring of the alien symbiote Venom. It bonded with the crazed serial killer, Cletus Kasady, thus creating one of Spider-Man's most murderous, brutal, and lethal adversaries.
After encountering the Kree hero Captain Marvel, Carol Danvers was accidentally subjected to otherworldly radiation that transformed her into a superhuman warrior. Calling herself Ms. Marvel, she established herself as one of the most powerful and prominent heroes and respected member of the Avengers. She has now adopted the mantle of Captain Marvel for herself.
Molten Man is the stepbrother of Liz Allen. He has had several run-ins with Spider-Man. He was recently cured of his condition.
Michelle is the sister of Vin Gonzales and Peter Parker's former roommate.
William ''Billy'' Connors is the son of Martha and Curt Connors (the Lizard).
Alistair Smythe is the son of Spencer Smythe: a mad scientist responsible for the creation of Spider-Slayers; robots designed to hunt and kill Spider-man. After his death Alistair carried on his work.
Madame web is a mutant with precognitive powers. She retains her powers after M-Day. Madame Web also is the one who reminds Peter Parker who he is when he starts to think about not being Spider-man. Was played by Stan Lee's wife Joan in the 90s cartoon.
Spider-Man villain with Hydrokinesis (the ability to control water), often part of teams with vendettas against the wall-crawler. Embodies the literal opposite of Spidey's other foe, Sandman.
Seymour was childhood friends with Peter Parker. He was later an admirer and close friend of Flash Thompson. He was eventually murdered by Venom
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