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Marla Jameson is the second wife of J. Jonah Jameson. She was a scientist specializing in robotics and helped create weapons to be used against Spider-Man - specifically the Spider-Slayers. When Smythe came after Jonah and his family, Marla was unfortunately killed by him.
A retired New York Police Department captain and the father of Gwen Stacy.
Max Modell was the head of Horizon Labs and also the employer and good friend of Peter Parker.
Roderick Kingsley became a worthy heir of the Goblin legacy, creating his own identity, of the Hobgoblin, rather than being just another Green Goblin clone.
The Jackal is an enemy of Spider-Man who played a big role in both of the Clone Sagas. He has since seemingly returned to infest Manhattan with spider-powers for his own sinister ends, organizing test subjects into a spider-powered army.
Harry Osborn's fiance who absorbed a unique variation of the Goblin Serum that allows her to shapeshift into a goblin. After losing those powers, she assumed the persona of Queen Cat.
Peter Parker's friend since college and Robbie Robertson's son.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
A career criminal, the man known as Rhino has incredible strength and durability. A long-time enemy of Spider-Man and the Incredible Hulk, Rhino isn't particularly malicious, and has tried on various occasions to leave behind his life of crime, but always seems to slide back into old habits.
The father of the former editor of The Daily Bugle, J. Jonah Jameson, and currently married to Peter Parker's Aunt May.
John Jameson is an astronaut, a test pilot and for his father J. Jonah Jameson the archetype of a true hero unlike these “masked clowns” like Spider-man. John has also been transformed into a Werewolf-like creature called the Man-Wolf, and was once host to the Carnage Symbiote.
MacDonald "Mac" Gargan was a failing private investigator that was turned into the Scorpion with financial help from J. Jonah Jameson. He became a host of the Venom symbiote and was part of Norman Osborn's Dark Avengers. After the US Government took the symbiote, he became The Scorpion once again.
Susan Storm is a founding member of the Fantastic Four and later the Future Foundation. She is able to create invisible force fields of any shape she conceives and able to turn herself and anything she's in contact with invisible. Sue is the wife of Reed Richards and the mother of their children, Franklin and Valeria.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
A long-lived mutant with the rage of a beast and the soul of a Samurai, James "Logan" Howlett's once mysterious past is filled with blood, war, and betrayal. Possessing an accelerated healing factor, keenly enhanced senses, and bone claws in each hand (along with his skeleton) that are coated in adamantium; Wolverine is, without question, the ultimate weapon.
A retired vaudevilian and love interest to Aunt May. He was also friends with Adrian Toomes, the original Vulture.
The second and most successful clone of Spider-Man created by the Jackal. A superhero known as the Scarlet Spider, Reilly later replaced Peter Parker for a time as Spider-Man after he found out that all this time he was the original and not Peter. Ben met his ultimate demise in the fight against the Green Goblin which led to Peter becoming Spider-Man once again, after he found out that he is the real Spider-Man after all.
Thor Odinson is the All-father of Asgard /God of Thunder, offspring of All-Father Odin & Elder-Goddess Gaea. Combining the powers of both realms makes him an elder-god hybrid and a being of no perceivable limits. Armed with his enchanted Uru hammer Mjolnir which helps him to channel his godly energies. The mightiest and the most beloved warrior in all of Asgard, a staunch ally for good and one of the most powerful beings in the multiverse/omniverse. Thor is also a founding member of the Avengers.
A journalist who worked at the Daily Bugle along with Peter Parker and after Civil War in Front Line newspaper. She seems to like sarcastic humor and Peter is usually the joke.
When U.S. Marine veteran Frank Castle's family's was murdered for witnessing a mob hit, the man vowed to avenge their deaths and became a one-man army in his personal war against the criminal underworld. With a distinct death's head skull adorning his chest, Frank Castle became the vigilante known as the Punisher.
Peter Parker's uncle and the father figure whose death was the main inspiration for Peter becoming Spider-Man. Ben Parker taught Peter that with great power comes great responsibility.
A famous big game hunter, who became a mercenary and later, developed an intense obsession with restoring honor to his name. Kraven has been known as a major threat for Spider-Man and leaving a legacy during his demise.
Kaine was the first clone of Spider-Man created by the Jackal. He was suffering from clone degeneration and became an assassin and spent years tormenting his clone brother, Ben Reilly. He has since taken up the mantle his now dead brother as the new Scarlet Spider.
As a child, Matt Murdock was blinded by radioactive waste while trying to save an elderly stranger about to get hit by a truck carrying the dangerous material. In turn, his other senses were heightened to superhuman sharpness and he gained a form of "radar sense". By day, he is a successful trial lawyer; but by night, he guards Hell's Kitchen as Daredevil: the Man Without Fear.
Lance Bannon was a former rival photographer of Peter Parker and boyfriend to Amy Powell. He was later murdered by the man known only as F.A.C.A.D.E.
A police officer in New York. Doesn't have faith that Spider-Man is a good guy.
Symkarian ruler and leader of a band of mercenaries known as the Wild Pack. More recently she has allied herself with Misty Knight, Paladin and the Heroes for Hire operation.
A small time criminal that worked his way up to having his own crime family within the Maggia.
A co-worker of Peter Parker's at Horizon Labs.
Son of Wilson and Vanessa Fisk. Took up the identity of The Rose to become a rival to his father, and later became Blood Rose to act as a vigilante who openly fought against his father.
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