If Spider-Man were to have existed in the DCU, before or after Flashpoint, who would he end up with. Here's my list of runner-ups:
Wonder Woman. Her stubbornness and strong-willed personality would be an interesting match for Peter, who is shy an nerdy.
Catwoman. A black cat stand-in, basically.
Kara Zor-El. She almost won. Something about her and Peter just works. But not as much as him and this next character . . .
The best love interest for Spider-Man in the DCU is . . .
Barbara Gordon A.K.A. Batgirl
In my opinion anyway.