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Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
Sasha was married to Kraven the Hunter.
Michelle is the sister of Vin Gonzales and Peter Parker's former roommate.
Victoria Hand was previously Norman Osborn's second in command, as Deputy Director of H.A.M.M.E.R. She was inducted into the New Avengers as Steve Rogers believed she deserved a second chance.
The amoral industrialist Norman Osborn was transformed by an experimental serum into the maniacal Green Goblin, and has endured over the decades as Spider-Man's most dreaded archenemy. Osborn is known for being the killer of Gwen Stacy, the architect of the Clone Saga, and the one-time director of S.H.I.E.L.D.
A journalist who worked at the Daily Bugle along with Peter Parker and after Civil War in Front Line newspaper. She seems to like sarcastic humor and Peter is usually the joke.
The father of the former editor of The Daily Bugle, J. Jonah Jameson, and currently married to Peter Parker's Aunt May.
Rumor monger and scandal sheet printer, Dexter Bennett became the latest owner of the Daily Bugle after a hostile buyout of long-time owner J. Jonah Jameson.
Former New York City Police Department officer and Peter Parker's ex-girlfriend. She was briefly transformed by the Goblin Serum, but has since been returned to normal.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
Kaine was the first clone of Spider-Man created by the Jackal. He was suffering from clone degeneration and became an assassin and spent years tormenting his clone brother, Ben Reilly. He has since taken up the mantle his now dead brother as the new Scarlet Spider.
Secretary to J. Jonah Jameson.
A former investigative journalist for the Daily Bugle and current owner of the newspaper Front Line who uses his friendships with Daredevil and Spider-Man to get information on criminals.
Among the most powerful, recognizable, and infamous mutants to inhabit the planet Earth, Magneto was the X-Men's first major nemesis. Now known as a revolutionist and terrorist, Magneto has fought for the X-Men as many times as he’s been against them.
Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after realising he was unhappy with his life. He joined the Avengers and later Silver Sable's Wild Pack. Sandman eventually returned to crime after being brainwashed by the Wizard, but sometimes still displays desire to better himself.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
A scientist who believes in predicting the future with math.
Editor-in-Chief of the Daily Bugle, and perhaps the best friend to J. Jonah Jameson.
Peter Parker's aunt-by-marriage and one of the most important people in his life.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
Quicksilver is a superhuman with the ability to travel at speeds far beyond the average human. He is the twin brother of the Scarlet Witch. After he and his sister left the Brotherhood of Evil Mutants, they became members of the Avengers. Although Quicksilver's loyalties and reliability have long been erratic, his love for his sister has proven constant.
The world knows Wanda Maximoff as the Scarlet Witch, with probability manipulation and reality-warping abilities. The twin sister of Quicksilver, mother to Wiccan and Speed, and ex-wife of the Vision; Wanda has taken on many roles throughout her life but will forever be known for causing the Decimation.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
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