In ultimate wolverine vs. Hulk, the hulk ripped him in half, he had to crawl over to his legs to collect them(claiming they would not regrow themselves), apparently he had planned to re-attach his spine to his pelvis himself(LoL?), but the hulk and later fury interveined. Then fury had Wolverines head removed, and it was still functional(he even tried to kill him by placing him in a vacuum, but this proved impossible because he came back to life as soon as he was taken out of the vacuum), talking and all. Later on in the story She-hulk rips his eye out, and in a conversartion with Banner he mentions it takes him longer to regrow a complex organ like an eye then simply healing normal wounds.
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