Hecate

She is variously associated with crossroads, entrance-ways, night, light, magic, witchcraft, knowledge of herbs and poisonous plants, ghosts, necromancy, and sorcery. Her earliest appearance in literature was in Hesiod's Theogony in the last third part of the 8th century BCE as a Titan goddess of great honor with domains in sky, earth, and sea. Her place of origin is debated by scholars, but she had popular followings amongst the witches of Thessaly and an important sanctuary among the Carians of Asia Minor in Lagina.

Hecate was one of several deities worshiped in ancient Athens as a protector of the oikos (household), alongside Zeus, Hestia, Hermes, and Apollo. In the post-Christian writings of the Chaldean Oracles (2nd–3rd century CE) she was also regarded with (some) rulership over earth, sea, and sky, as well as a more universal role as Savior (Soteira), Mother of Angels and the Cosmic World Soul. Regarding the nature of her cult, it has been remarked, "she is more at home on the fringes than in the center of Greek polytheism. Intrinsically ambivalent and polymorphous, she straddles conventional boundaries and eludes definition."

DC Comics: New 52's Wonder Woman

Goddess of magic. She was persecuted for how she looked, but fell in love with Zeus when he saw her for a woman. She pretended to help Wonder Woman while planning to steal Baby Zeke because he was the reincarnation of the man she once loved.

DC Comics: Superman and Silver Banshee

A sorceress who kidnapped Lois Lane. Superman and Silver Banshee teamed up to stop her. A man named Thorpe worked for her.

Dark Horse

In the Hellboy comics she tried to push him to his destiny as the Beast of the Apocalypse.

Marvel

Hecate rescued the elementals (Hellfire, Magnum, Hydron, and Zephyr) from space. After she rescued them she finds out they are after a powerful ruby scarab and goes to stop them from getting it. Meanwhile Ms. Marvel had a prediction that her friend Salia Petrie's death on a space shuttle. She goes to save her friend and encounters Hecate and the Elementals. Hecate thinks that Ms. Marvel is also after the scarab and the two start to fight. As the two are fighting the Elementals find the scarab and uses it to levitate a small island to crush the two women. Hecate uses one mind blast to destroy the island and the blast accidentally kills Salia petrie as Ms. Marvel had predicted. Hecate realized that Ms. Marvel only wanted to save her friend and the two team up and defeat the Elementals. Ms. Marvel then regressed to Carol Danvers and she steals the scarab to use it against Hecate. But the scarab merged the two personalities and she forgave Hecate for the death of her friend. Hecate took the scarab to keep it out of the wrong hands.

She later fought Hercules.