How could Albert Wesker be Introduced and Adapt in the Follpwing Comic Universes?

Marvel:

-Earth 616

-Ultimate Universe

DC:

-New 52

-Pre New 52

-Pre Crisis

-Rebirth

IDW:

-Godzilla

-GI Joe

-Judge Dredd

-TMNT (can't remember if it was part of IDW)

-Hellboy (the same with Hellboy)

-Alien vs Predator (and Alien vs Predator)

How could he be introduced from the begining or in the present?

Who would be his main enemy (maybe batman or Captain America?), and his regular enemies?

How would he adapt to events (like civil war or infinite crisis)

Who would he ally with?

Would his character change a lot?

So you want how he would fit in to these scenarios? like he would probably work for weyland in avp universe.

Or is he supposed to have any particulars cuz I'm not familiar with all these

I could see him being Intergang or Checkmate or working for Waller in DC